7 days in Southeast Florida Itinerary

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Key West is known for museums, adventure, and wildlife. Your trip includes some of its best attractions: see the interesting displays at The Ernest Hemingway Home and Museum, contemplate the long history of Curry Mansion Inn, view the masterpieces at Alan S. Maltz Gallery, and look for gifts at Peppers of Key West.

To see where to stay, reviews, traveler tips, and tourist information, refer to the Key West vacation site.

Los Angeles to Key West is an approximately 9-hour flight. You can also drive; or take a bus. Due to the time zone difference, you'll lose 3 hours traveling from Los Angeles to Key West. Traveling from Los Angeles in September, Key West is somewhat warmer at night with lows of 80°F. Finish your sightseeing early on the 20th (Sun) so you can drive to Islamorada.

Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.

Start off your visit on the 21st (Mon): stop by Bella Sol Fragrance Bar and Gifts, sample the tasty concoctions at Florida Keys Brewing Company, then see what you can catch with a fishing tour, and finally soothe aching muscles at Island Flow Yoga.

Plan a Islamorada trip in moments using our itinerary builder.

You can drive from Key West to Islamorada in 2 hours. Another option is to take a bus. In September, daily temperatures in Islamorada can reach 90°F, while at night they dip to 79°F. Wrap up your sightseeing on the 21st (Mon) to allow time to drive to Key Largo.

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.

Kick off your visit on the 22nd (Tue): get up close and personal with brilliant marine life at Island Dolphin Care, then get outside with JSK Watersports, then relax and rejuvenate at Key Largo Yoga, and finally get the adrenaline pumping with Jetpack Water Flights.

To plan Key Largo vacation without wasting time, ask Inspirock to design an itinerary.

Key Largo is very close to Islamorada. In September, daily temperatures in Key Largo can reach 88°F, while at night they dip to 76°F. Finish up your sightseeing early on the 22nd (Tue) so you can go by car to Miami.

Florida’s mecca of fun in the sun, the lively tropical metropolis of Miami is one of the world’s top vacation spots.

Start off your visit on the 23rd (Wed): get to know the fascinating history of Art Deco Historic District, enjoy the sand and surf at South Beach, then take a stroll through Lincoln Road, and finally enjoy some diversion at Lock & Load Miami.

For traveler tips, where to stay, maps, and other tourist information, use the Miami road trip app.

Traveling by car from Key Largo to Miami takes 1.5 hours. Alternatively, you can take a bus. In September, daily temperatures in Miami can reach 90°F, while at night they dip to 77°F. Finish up your sightseeing early on the 23rd (Wed) so you can catch the flight back home.