7 days in Southeast Florida Itinerary

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Key West is known for wildlife, adventure, and museums. Your plan includes some of its best attractions: see some colorful creatures with a scuba or snorkeling tour, kick back and relax at Fort Zachary Taylor, look for all kinds of wild species at Key West Butterfly & Nature Conservatory, and make a trip to Duval Street.

To see more things to do, traveler tips, and more tourist information, read our Key West journey planner.

Los Angeles to Key West is an approximately 10-hour flight. You can also drive; or take a bus. The time zone changes from Pacific Standard Time to Eastern Standard Time, which is usually a 3 hour difference. Traveling from Los Angeles in September, Key West is a bit warmer at night with lows of 80°F. Finish your sightseeing early on the 20th (Sun) to allow enough time to drive to Islamorada.

Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.

Start off your visit on the 21st (Mon): stop by Bella Sol Fragrance Bar and Gifts, sample the tasty concoctions at Florida Keys Brewing Company, then see what you can catch with a fishing tour, and finally soothe aching muscles at Island Flow Yoga.

Plan a Islamorada trip in moments using our itinerary builder.

You can drive from Key West to Islamorada in 2 hours. Another option is to take a bus. In September, daily temperatures in Islamorada can reach 90°F, while at night they dip to 79°F. Wrap up your sightseeing on the 21st (Mon) to allow time to drive to Key Largo.

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.

Kick off your visit on the 22nd (Tue): get up close and personal with brilliant marine life at Island Dolphin Care, take a memorable tour with JSK Watersports, relax and rejuvenate at Key Largo Yoga, then push the limits with Jetpack Water Flights, and finally grab your bike and head to Florida Keys Visitor Center.

To see traveler tips, other places to visit, reviews, and more tourist information, read our Key Largo trip planner.

Key Largo is very close to Islamorada. Expect a daytime high around 88°F in September, and nighttime lows around 76°F. Finish your sightseeing early on the 22nd (Tue) so you can drive to Miami.

Florida’s mecca of fun in the sun, the lively tropical metropolis of Miami is one of the world’s top vacation spots.

Start off your visit on the 23rd (Wed): get to know the fascinating history of Art Deco Historic District, enjoy the sand and surf at South Beach, then take a stroll through Lincoln Road, and finally enjoy some diversion at Lock & Load Miami.

For traveler tips, where to stay, maps, and other tourist information, use the Miami road trip app.

Traveling by car from Key Largo to Miami takes 1.5 hours. Alternatively, you can take a bus. In September, daily temperatures in Miami can reach 90°F, while at night they dip to 77°F. Finish up your sightseeing early on the 23rd (Wed) so you can travel back home.