58 days in South America Itinerary
Created using Inspirock South America route planner
Start: San Francisco, United States
Fly to San Cristóbal Airport, Drive to Puerto Baquerizo Moreno
1
Puerto Baquerizo Moreno, Ecuador
— 5 nights
Ferry
2
Puerto Ayora, Ecuador
— 5 nights
Ferry
3
Puerto Villamil, Ecuador
— 4 nights
Fly to Baltra Island, Fly to Cusco
4
Cusco, Peru
— 6 nights
Fly
5
Santiago, Chile
— 4 nights
Fly
6
Buenos Aires, Argentina
— 4 nights
+2
Fly to Rio De Janeiro-Galeao, Bus to Conceição de Jacareí, Ferry to Ilha Grande
7
Ilha Grande, Brazil
— 6 nights
Ferry to Angra dos Reis, Drive to Paraty
8
Paraty, Brazil
— 5 nights
Drive
9
Rio de Janeiro, Brazil
— 6 nights
Fly
10
Fernando de Noronha, Brazil
— 7 nights
Fly to Brasilia, Bus to Alto Paraiso de Goias
11
Alto Paraiso de Goias, Brazil
— 5 nights
Bus to Brasília, Fly to San Francisco
End: San Francisco, United States
Sun, Jul 17 - Mon, Sep 12
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Puerto Baquerizo Moreno, Ecuador — 5 nights

The capital of the Galapagos Islands, Puerto Baquerizo Moreno is located on easternmost island of the archipelago, San Cristobal.Step out of the city life by going to Cerro Tijeretas and La Loberia. Your cultural itinerary includes sights like Interpretation Center and Catedral Inmaculada Concepcion. There's lots more to do: see some colorful creatures with Wreck Bay Diving Center, kick back and relax at Punta Pitt, and stroll through Playa Mann.
To see photos, maps, ratings, and more tourist information, read our Puerto Baquerizo Moreno trip itinerary builder.
San Francisco, USA to Puerto Baquerizo Moreno is an approximately 20-hour combination of flight and car. You'll lose 3 hours traveling from San Francisco to Puerto Baquerizo Moreno due to the time zone difference. Prepare for somewhat warmer weather when traveling from San Francisco in July: high temperatures in Puerto Baquerizo Moreno hover around 80°F and lows are around 71°F. Wrap up your sightseeing on the 22nd (Fri) to allow time to ride a ferry to Puerto Ayora.
Side Trip
Find places to stay Jul 17 — 22:
Highlights from your trip
Puerto Ayora, Ecuador — 5 nights

The largest settlement in the Galapagos, Puerto Ayora offers visitors to the islands an array of facilities and things to do.Escape the urban bustle at Charles Darwin Research Station and Galapagos Beach at Tortuga Bay. Change things up with a short trip to Metropolitan Touring in Baltra (about 1h 20 min away). Next up on the itinerary: tour the pleasant surroundings at El Chato - Giant Tortoise Reserve, enjoy the sand and surf at Playa de los Alemanes, contemplate the waterfront views at Canal de Itabaca, and take in the exciting artwork at Samay Latin Art.
To find traveler tips, photos, other places to visit, and tourist information, go to the Puerto Ayora trip itinerary app.
Traveling by ferry from Puerto Baquerizo Moreno to Puerto Ayora takes 3.5 hours. In July, plan for daily highs up to 80°F, and evening lows to 71°F. Finish your sightseeing early on the 27th (Wed) to allow enough time to ride a ferry to Puerto Villamil.
Side Trips
Find places to stay Jul 22 — 27:
Highlights from your trip
Puerto Villamil, Ecuador — 4 nights
Located in the southeast of Isla Isabela, Puerto Villamil is home to the majority of the island's 2,200 inhabitants.Step out of the city life by going to Sierra Negra and Rosedelco- Day tour. Next up on the itinerary: identify plant and animal life at Los Tuneles, trek along Pozas verde, and enjoy the sand and surf at Playa Puerto Villamil.
To see more things to do, reviews, other places to visit, and other tourist information, use the Puerto Villamil day trip planning site.
Traveling by ferry from Puerto Ayora to Puerto Villamil takes 3.5 hours. You'll gain 1 hour traveling from Puerto Ayora to Puerto Villamil due to the time zone difference. Finish your sightseeing early on the 31st (Sun) to allow enough time to travel to Cusco.
Side Trip
Find places to stay Jul 27 — 31:
Highlights from your trip
Cusco, Peru — 6 nights

Imperial City
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.Take a break from the city and head to Salinas de Maras and Nature & Wildlife Tours. Sacsayhuaman and Plaza de Armas are good opportunities to explore the local culture. Step out of Cusco to go to Maras and see Moray, which is approximately 1h 20 min away. There's much more to do: take in the spiritual surroundings of Qorikancha, hike along exploor, explore the world behind art at Museo de Arte Precolombino, and take an in-depth tour of Museo de Vida Monastica - Monasterio de Santa Catalina del Cusco.
Plan my Cusco trip by asking Inspirock to come up with tips and suggestions.
You can fly from Puerto Villamil to Cusco in 14 hours. The time zone difference moving from Galapagos Time (GALT) to Peru Standard Time (PET) is 1 hour. July in Cusco sees daily highs of 69°F and lows of 34°F at night. Finish your sightseeing early on the 6th (Sat) to allow enough time to fly to Santiago.
Side Trip
Find places to stay Jul 31 — Aug 6:
Highlights from your trip
Santiago, Chile — 4 nights

City of the Island Hills
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.Get in touch with nature at San Cristóbal Hill and Valle Nevado - Ski Resort Chile. Satisfy your inner culture vulture at Concha y Toro and Museo Interactivo Mirador. There's much more to do: stroll around Cerro Santa Lucia, get engrossed in the history at Museo Colchagua, examine the collection at La Chascona, and admire the striking features of Metropolitan Cathedral (Catedral Metropolitana).
For traveler tips, more things to do, photos, and other tourist information, go to the Santiago attractions planner.
You can fly from Cusco to Santiago in 6.5 hours. Other options are to drive; or take a bus. The time zone changes from Peru Standard Time to Chile Standard Time, which is usually a 1 hour difference. Finish up your sightseeing early on the 10th (Wed) so you can catch the flight to Buenos Aires.
Side Trips
Find places to stay Aug 6 — 10:
Highlights from your trip
Buenos Aires, Argentina — 4 nights

Queen of La Plata
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.Do some cultural sightseeing at Cementerio de la Recoleta and Parque 3 de Febrero. Deepen your sense of the past at sights like Calle Defensa and Plaza de Mayo. The adventure continues: wander the streets of Puerto Madero, steep yourself in history at Museo Histórico Nacional del Cabildo y la Revolución de Mayo, pause for some serene contemplation at Catedral Primada, and get engrossed in the history at El Zanjon de Granados.
To find photos, other places to visit, where to stay, and more tourist information, read Buenos Aires itinerary builder tool.
Traveling by flight from Santiago to Buenos Aires takes 5.5 hours. Alternatively, you can drive; or take a bus. The time zone changes from Chile Standard Time (CLT) to Argentina Standard Time (ART), which is usually a 1 hour difference. In August, daily temperatures in Buenos Aires can reach 63°F, while at night they dip to 51°F. Wrap up your sightseeing by early afternoon on the 14th (Sun) to allow time for travel to Ilha Grande.
Find places to stay Aug 10 — 14:
Highlights from your trip
Ilha Grande, Brazil — 6 nights
A tumultuous and unsavory history has kept Ilha Grande relatively undeveloped and free of the trappings of the modern world.Visiting Pico do Papagaio and Aracatibinha Beach will get you outdoors. Satisfy your inner culture vulture at Aquamarina Mergulho and Parnaioca Beach. There's lots more to do: relax and rejuvenate at Ilha Grande Yoga, examine the collection at Ecomuseu Ilha Grande, kick back and relax at Dois Rios Beach, and delve into the distant past at Ruinas do Lazareto.
Quickly create a custom-made itinerary for Ilha Grande using our trip planner.
Do a combination of flight, bus, and ferry from Buenos Aires to Ilha Grande in 11 hours. Alternatively, you can do a combination of car and ferry; or do a combination of bus and ferry. Plan for somewhat warmer temperatures traveling from Buenos Aires in August, with highs in Ilha Grande at 80°F and lows at 62°F. Cap off your sightseeing on the 20th (Sat) early enough to travel to Paraty.
Find places to stay Aug 14 — 20:
Highlights from your trip
Paraty, Brazil — 5 nights

Gazing out over a bay of tiny tropical islands, with rainforests climbing mountains in the background, it's easy to see why tourism in Paraty gets more popular by the year.Get in touch with nature at Centro Historico and Horseback Riding Tours. Popular historic sites such as Church of Our Lady of Penha and The Gold Path are in your itinerary. And it doesn't end there: take in the awesome beauty at Pao de Acucar Peak, get to know the fascinating history of Estrada Real, tour the pleasant surroundings at Saco do Mamangua Beach, and take a tour by water with Boat Tours & Water Sports.
To find where to stay, traveler tips, maps, and other tourist information, use the Paraty trip tool.
Do a combination of ferry and car from Ilha Grande to Paraty in 3 hours. Alternatively, you can do a combination of ferry and bus. Finish your sightseeing early on the 25th (Thu) so you can drive to Rio de Janeiro.
Find places to stay Aug 20 — 25:
Highlights from your trip
Rio de Janeiro, Brazil — 6 nights

Marvelous City
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.Popular historic sites such as Ilha Fiscal and Parque Lage are in your itinerary. Get some cultural insight at Copacabana Beach and Pedra Bonita. And it doesn't end there: kick back and relax at Praia de Ipanema, tour the pleasant surroundings at Mirante da Prainha, make a trip to Escadaria Selaron, and glide through the air with a parasailing or paragliding tour.
To find photos, reviews, and more tourist information, use the Rio de Janeiro driving holiday site.
Traveling by car from Paraty to Rio de Janeiro takes 4 hours. Alternatively, you can do a combination of taxi and bus; or take a bus. In August, plan for daily highs up to 79°F, and evening lows to 66°F. Finish your sightseeing early on the 31st (Wed) so you can fly to Fernando de Noronha.
Find places to stay Aug 25 — 31:
Highlights from your trip
Fernando de Noronha, Brazil — 7 nights

Emerald of the Atlantic
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.Satisfy your inner culture vulture at Aulas de Energia – Espaco Usina Solar Fernando de Noronha and Shark Museum. Visiting Baia do Sancho and Praia do Sueste will get you outdoors. And it doesn't end there: kick back and relax at Baia dos Porcos, stroll through Praia do Leão, hike along Trilha Costa Esmeralda, and explore the striking landscape at Morro dois Irmaos.
To see photos, other places to visit, maps, and more tourist information, read our Fernando de Noronha online trip planner.
Traveling by flight from Rio de Janeiro to Fernando de Noronha takes 7 hours. You'll lose 1 hour traveling from Rio de Janeiro to Fernando de Noronha due to the time zone difference. Traveling from Rio de Janeiro in August, plan for a bit warmer nights in Fernando de Noronha, with lows around 76°F. Wrap up your sightseeing by early afternoon on the 7th (Wed) to allow time for travel to Alto Paraiso de Goias.
Find places to stay Aug 31 — Sep 7:
Highlights from your trip
Alto Paraiso de Goias, Brazil — 5 nights

Highland Paradise
Developed from a 19th-century cattle ranch, Alto Paraiso de Goias serves as the major gateway to a World Heritage-listed national park known for containing some of the world's oldest natural rock formations.Escape the urban bustle at Parque Nacional da Chapada dos Veadeiros and Catarata dos Couros. There's much more to do: hike along Sertao Zen, whizz through the canopy at some of the top local zipline courses and adventure parks, take in the dramatic scenery at Vale do Rio Macaco waterfall, and contemplate the waterfront views at Vale da Lua.
To see photos, where to stay, and other tourist information, read Alto Paraiso de Goias sightseeing planner.
You can do a combination of flight and bus from Fernando de Noronha to Alto Paraiso de Goias in 11.5 hours. The time zone changes from Fernando de Noronha Standard Time (FNT) to Amazon Standard Time (AMT), which is usually a -2 hour difference. Finish your sightseeing early on the 12th (Mon) so you can travel back home.
Find places to stay Sep 7 — 12:
Highlights from your trip