5 days in Roanoke, Myrtle Beach & Knoxville Itinerary

5 days in Roanoke, Myrtle Beach & Knoxville Itinerary

Created using Inspirock United States vacation planner

Plan created by another user. Make it yours
1
Roanoke
— 1 night
Fly
2
Myrtle Beach
— 2 nights
Fly
3
Knoxville
— 1 night

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1
night
Roanoke

Roanoke is an independent city in the U.S. On the 5th (Sat), examine the collection at Virginia Museum of Transportation, browse for treasures at Black Dog Salvage, then stroll around Mill Mountain Star & Park, and finally contemplate in the serene atmosphere at St. John's Episcopal Church. On the 6th (Sun), you'll have a packed day of sightseeing: pause for some photo ops at National D-Day Memorial and then explore the world behind art at Taubman Museum of Art.

For maps, traveler tips, where to stay, and other tourist information, read Roanoke trip planning tool.

Use the Route module to find suitable travel options from your home destination to Roanoke. In September, daily temperatures in Roanoke can reach 80°F, while at night they dip to 60°F. Finish your sightseeing early on the 6th (Sun) to allow enough time to drive to Myrtle Beach.

Things to do in Roanoke

Museums · Parks · Shopping · Historic Sites

Side Trip

Find places to stay Sep 5 — 6:

2
nights
Myrtle Beach

Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Kick off your visit on the 7th (Mon): take a tour by water with Boat Tours & Water Sports, stroll through Myrtle Beach, and then catch some excitement at Myrtle Beach SkyWheel. On the 8th (Tue), you'll have a packed day of sightseeing: admire nature's wide array of creatures at Ripley's Aquarium of Myrtle Beach and then get a taste of the local shopping with Broadway at the Beach.

For ratings, traveler tips, more things to do, and more tourist information, read our Myrtle Beach vacation builder.

You can fly from Roanoke to Myrtle Beach in 6 hours. Alternatively, you can drive; or fly; or do a combination of train and car. Plan for a bit warmer nights when traveling from Roanoke in September since evenings lows in Myrtle Beach dip to 69°F. Finish your sightseeing early on the 8th (Tue) so you can travel to Knoxville.

Things to do in Myrtle Beach

Parks · Outdoors · Beaches · Neighborhoods
Find places to stay Sep 6 — 8:

1
night
Knoxville

Marble City

A gateway to Great Smoky Mountains National Park, Knoxville embraces music culture.
Kick off your visit on the 9th (Wed): don't miss a visit to First Baptist Church, then take an in-depth tour of East Tennesse Historical Society, and then don't miss a visit to Market Square.

To see maps, other places to visit, traveler tips, and tourist information, go to the Knoxville trip itinerary maker site.

Traveling by flight from Myrtle Beach to Knoxville takes 5 hours. Alternatively, you can fly; or drive; or take a bus. Traveling from Myrtle Beach in September, Knoxville is slightly colder at night with lows of 62°F.

Things to do in Knoxville

Museums · Historic Sites
Find places to stay Sep 8 — 9: