22 days in Italy & Austria Itinerary

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.

Rome is known for historic sites, museums, nightlife, shopping, and classes. Your plan includes some of its best attractions: explore the ancient world of Colosseum, get to know the fascinating history of Piazza Navona, contemplate the long history of Palatine Hill, and admire the masterpieces at Vatican Museums.

For maps, more things to do, and more tourist information, use the Rome trip builder website .

Washington DC, USA to Rome is an approximately 13-hour combination of subway, bus, and flight. You can also do a combination of train and flight; or do a combination of subway, bus, flight, and train. The time zone difference when traveling from Washington DC to Rome is 6 hours. In April, daily temperatures in Rome can reach 69°F, while at night they dip to 49°F. Finish your sightseeing early on the 14th (Sat) to allow enough time to travel to Amalfi.

Known for its impressive hillside cascade of colorful stone buildings down to the Mediterranean shore, Amalfi is the cultural and commercial heart of southern Italy's Amalfi Coast.

Dedicate the 15th (Sun) to wine at some of the top wineries in the area. There's much more to do: get to know the fascinating history of Centro Storico Ravello, admire the landmark architecture of Villa Rufolo, look for gifts at La Bottega delle Arti, and steep yourself in history at Duomo di Ravello.

To find reviews, traveler tips, other places to visit, and more tourist information, refer to the Amalfi trip itinerary planner .

You can do a combination of train, subway, and taxi from Rome to Amalfi in 3 hours. Other options are to drive; or do a combination of train and bus. Traveling from Rome in April, plan for a bit warmer nights in Amalfi, with lows around 59°F. Wrap up your sightseeing by early afternoon on the 17th (Tue) to allow time for travel to Florence.

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.

Florence is known for museums, historic sites, shopping, classes, and nightlife. Your plan includes some of its best attractions: admire the masterpieces at Uffizi Galleries, admire the natural beauty at The Boboli Gardens, take in the spiritual surroundings of Cathedral of Santa Maria del Fiore, and take some stellar pictures from Piazzale Michelangelo.

To see reviews, traveler tips, photos, and tourist information, refer to the Florence road trip app .

Do a combination of taxi, subway, and train from Amalfi to Florence in 4.5 hours. Alternatively, you can drive; or do a combination of bus, train, and flight. Plan for little chillier nights when traveling from Amalfi in April since evenings lows in Florence dip to 50°F. Wrap up your sightseeing on the 20th (Fri) to allow time to take a train to Milan.

In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.

Kick off your visit on the 21st (Sat): admire the landmark architecture of Galleria Vittorio Emanuele II, then pause for some serene contemplation at Duomo di Milano, and then stroll the grounds of Monumental Cemetery.

Plan my trip to Milan with suggested itineraries provided by Inspirock.

Traveling by train from Florence to Milan takes 2 hours. Alternatively, you can drive; or take a bus. Expect a daytime high around 67°F in April, and nighttime lows around 49°F. Finish your sightseeing early on the 21st (Sat) to allow enough time to take a train to Venice.

Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.

Step out of Venice with an excursion to Scrovegni Chapel in Padua--about 52 minutes away. Next up on the itinerary: explore the activities along Canal Grande, admire the striking features of Doge's Palace, explore the world behind art at Gallerie dell'Accademia, and snap pictures at Ponte dei Sospiri.

For where to stay, traveler tips, more things to do, and more tourist information, go to the Venice itinerary planning site .

Take a train from Milan to Venice in 2.5 hours. Alternatively, you can drive; or take a bus. In April, plan for daily highs up to 65°F, and evening lows to 49°F. Finish your sightseeing early on the 25th (Wed) so you can travel to Vienna.

The cultural, economic, and political center of the country, Vienna has developed from its early Celtic and Roman roots into a medieval and Baroque city, with an old town that was designated a World Heritage Site in 2001.

Vienna is known for museums, parks, nightlife, historic sites, and zoos & aquariums. Your plan includes some of its best attractions: stroll through Schonbrunn Palace, examine the collection at MuseumsQuartier Wien, get a new perspective on nature at Natural History Museum (Naturhistorisches Museum), and explore the world behind art at Kunsthistorisches Museum Wien.

For ratings, photos, reviews, and more tourist information, use the Vienna trip itinerary builder site .

You can fly from Venice to Vienna in 4 hours. Alternatively, you can drive; or take a train. Traveling from Venice in April, you can expect nighttime temperatures to be a bit cooler in Vienna, with lows of 42°F. Wrap up your sightseeing on the 29th (Sun) early enough to travel to Salzburg.

Surrounded by mountain ranges and boasting a well-preserved city center, Salzburg melds culture and history.

Salzburg is known for historic sites, museums, parks, nightlife, and nature. Your plan includes some of its best attractions: get great views at Salzburg Fortress (Festung Hohensalzburg), see the interesting displays at Salzburg Museum, explore the historical opulence of Schloss Hellbrunn, and explore the galleries of Mozart Residence (Mozart Wohnhaus).

For traveler tips, more things to do, reviews, and tourist information, refer to the Salzburg tour itinerary website .

You can fly from Vienna to Salzburg in 2.5 hours. Alternatively, you can take a train; or drive. April in Salzburg sees daily highs of 58°F and lows of 40°F at night. Finish your sightseeing early on the 1st (Tue) to allow enough time to travel back home.