21 days in Spain, France & Italy Itinerary

21 days in Spain, France & Italy Itinerary

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Route & dates

21 days in Spain, France & Italy Itinerary

Start: Boston, United States
Fly:  10​h
1
Madrid, Spain
— 2 nights
2
Barcelona, Spain
— 4 nights
train:  5​h 30​min
3
Paris, France
— 2 nights
train:  5​h
4
Venice, Italy
— 4 nights
5
Florence, Italy
— 3 nights
bus:  2​h
6
Rome, Italy
— 3 nights
Fly:  12​h 30​min
End: Boston, United States

2
nights
Madrid, Spain

Madrid ©
Madrid is known for its cultural and artistic heritage, lively nightlife, and a dynamic culinary scene.
Prado National Museum and Catedral de Segovia are good opportunities to explore the local culture. Royal Palace of Madrid and Alcazar de Segovia will appeal to museum buffs. You'll find plenty of places to visit near Madrid: Monastery of San Juan de los Reyes (in Toledo) and The Walls of Avila (in Avila). There's more to do: examine the collection at Museo Nacional Thyssen-Bornemisza and admire the masterpieces at Museo Sorolla.

To find ratings, more things to do, traveler tips, and more tourist information, read Madrid trip maker site .

Boston, USA to Madrid is an approximately 10-hour flight. The time zone difference moving from Eastern Standard Time (EST) to Central European Time (CET) is 6 hours. While traveling from Boston, expect a bit warmer days and about the same nights in Madrid, ranging from highs of 73°F to lows of 53°F. On the 21st (Mon), wrap the sightseeing up by early afternoon so you can take a train to Barcelona.

Things to do in Madrid

Museums Historic Sites

Side Trips

Segovia, The Walls of Avila, Monastery of San Juan de los Reyes
Find places to stay Oct 19 — 21:
Highlights from your plan
Prado National Museum ©
Prado National Museum
The Walls of Avila ©
The Walls of Avila
Catedral de Segovia ©
Catedral de Segovia

4
nights
Barcelona, Spain

Barcelona ©
Barcelona, the country’s second-largest city, is a cosmopolitan urban center known for its throbbing youthful energy and stellar architecture.
Museum-lovers will get to explore Casa Batllo and Carrer del Mirador del Palau Nacional. Discover out-of-the-way places like Girona Cathedral (Catedral) and Casa Mila - La Pedrera. Step out of Barcelona with an excursion to Patronat Call de Girona in Girona--about 1h 20 min away. There's much more to do: make a trip to Basilica of the Sagrada Familia, explore the world behind art at Museu Picasso, take an in-depth tour of Museu d'Història de Barcelona MUHBA, and take a stroll through El Barri Gòtic.

To see reviews, photos, maps, and more tourist information, refer to the Barcelona driving holiday planning app .

Getting from Madrid to Barcelona by train takes about 3 hours. Other options: fly; or drive. Expect somewhat warmer evenings in Barcelona when traveling from Madrid in October, with lows around 60°F. Finish your sightseeing early on the 25th (Fri) to allow enough time to travel to Paris.

Things to do in Barcelona

Museums Historic Sites Neighborhoods

Side Trip

Girona
Find places to stay Oct 21 — 25:
Highlights from your plan
Casa Batllo ©
Casa Batllo
Basilica of the Sagrada Familia ©
Basilica of the Sagrada Familia
El Barri Gòtic ©
El Barri Gòtic

2
nights
Paris, France

Paris ©
A beautiful and romantic city fit for any itinerary, Paris brims with historic associations and remains vastly influential in the realms of culture, art, fashion, food and design.
Museum-lovers will get to explore Louvre Museum and Musee d'Orsay. Satisfy your inner culture vulture at Eiffel Tower and Basilique du Sacre-Coeur de Montmartre. Step out of Paris with an excursion to Palace of Versailles in Versailles--about 48 minutes away. Next up on the itinerary: appreciate the history behind Arc de Triomphe, take a stroll through Trocadero, appreciate the extensive heritage of Montmartre, and head off the coast to Île de la Cité.

For photos, where to stay, maps, and other tourist information, you can read our Paris trip itinerary planner.

You can fly from Barcelona to Paris in 5 hours. Alternatively, you can do a combination of train and flight; or drive. Expect little chillier temperatures when traveling from Barcelona in October; daily highs in Paris reach 62°F and lows reach 48°F. Wrap up your sightseeing on the 27th (Sun) early enough to travel to Venice.

Things to do in Paris

Historic Sites Museums Neighborhoods

Side Trip

Palace of Versailles
Find places to stay Oct 25 — 27:
Highlights from your plan
Louvre Museum ©
Louvre Museum
Eiffel Tower ©
Eiffel Tower
Palace of Versailles ©
Palace of Versailles

4
nights
Venice, Italy

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Get a sense of the local culture at Doge's Palace and Basilica di San Marco. Eschew the tourist crowds and head to San Giorgio Maggiore and Cannaregio. Explore the numerous day-trip ideas around Venice: Padua (Orto Botanico di Padova, Basilica di Santa Giustina, & more) and Verona (San Fermo Maggiore, Verona, Piazzale Castel San Pietro, & more). There's much more to do: appreciate the extensive heritage of Piazza San Marco, make a trip to Church of San Pantalon, browse the exhibits of Peggy Guggenheim Collection, and contemplate the waterfront views at Canal Grande.

To find other places to visit, maps, photos, and tourist information, use the Venice trip itinerary site .

You can fly from Paris to Venice in 5 hours. Other options are to do a combination of train and flight; or drive. In October in Venice, expect temperatures between 66°F during the day and 51°F at night. Finish your sightseeing early on the 31st (Thu) so you can take a train to Florence.

Things to do in Venice

Historic Sites Museums Parks

Side Trips

Verona, Padua
Find places to stay Oct 27 — 31:
Highlights from your plan
Doge's Palace ©
Doge's Palace
Piazza San Marco ©
Piazza San Marco
Peggy Guggenheim Collection ©
Peggy Guggenheim Collection

3
nights
Florence, Italy

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Piazza del Duomo and Cathedral of Santa Maria del Fiore will appeal to history buffs. Satisfy your inner culture vulture at Gallerie Degli Uffizi and Academy Of Florence Art Gallery. Step out of Florence to go to Pisa and see Duomo di Pisa, which is approximately 1h 10 min away. And it doesn't end there: get to know the fascinating history of Centro Storico, explore the world behind art at Church and Museum of Orsanmichele, take in the spiritual surroundings of The Baptistery of St. John, and take an in-depth tour of Basilica di Santa Croce.

For where to stay, reviews, photos, and more tourist information, you can read our Florence trip itinerary builder .

Traveling by train from Venice to Florence takes 2.5 hours. Alternatively, you can drive; or take a bus. In October, daytime highs in Florence are 71°F, while nighttime lows are 54°F. Finish your sightseeing early on the 3rd (Sun) so you can take a train to Rome.

Things to do in Florence

Historic Sites Museums

Side Trip

Duomo di Pisa
Find places to stay Oct 31 — Nov 3:
Highlights from your plan
Piazza del Duomo ©
Piazza del Duomo
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi
Centro Storico ©
Centro Storico

3
nights
Rome, Italy

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Museum-lovers will appreciate Vatican Museums and Museo Nazionale Romano - Palazzo Massimo alle Terme. Discover out-of-the-way places like Palatine Hill and Galleria Borghese. There's much more to do: steep yourself in history at St. Peter's Basilica, delve into the distant past at Colosseum, take in the spiritual surroundings of Chiesa di Sant'Ignazio di Loyola, and pause for some serene contemplation at Pantheon.

For where to stay, ratings, traveler tips, and more tourist information, read our Rome visit planner.

Take a train from Florence to Rome in 2 hours. Alternatively, you can drive; or fly. In November in Rome, expect temperatures between 63°F during the day and 47°F at night. Finish your sightseeing early on the 6th (Wed) to allow enough time to travel back home.

Things to do in Rome

Historic Sites Museums

Side Trip

Vatican City
Find places to stay Nov 3 — 6:
Highlights from your plan
Palatine Hill ©
Palatine Hill
Colosseum ©
Colosseum
Pantheon ©
Pantheon

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